{"id":361,"date":"2019-01-19T16:57:54","date_gmt":"2019-01-19T16:57:54","guid":{"rendered":"http:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/?p=361"},"modified":"2019-01-19T16:57:54","modified_gmt":"2019-01-19T16:57:54","slug":"notes-on-resemblance-among-relatives-evolution-of-quantitative-traits-and-association-mapping","status":"publish","type":"post","link":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/2019\/01\/19\/notes-on-resemblance-among-relatives-evolution-of-quantitative-traits-and-association-mapping\/","title":{"rendered":"Notes on resemblance among relatives, evolution of quantitative traits, and association mapping"},"content":{"rendered":"<p>I just added three more sets of notes to the website:<\/p>\n<ol>\n<li>Resemblance among relatives &#8211; The mathematical underpinnings of how we use resemblance among relatives to estimate components of the genetic variance when we don&#8217;t know the underlying genes.<\/li>\n<li>Evolution of quantitative traits &#8211; The mathematics of how selection on phenotypes results in changes in allele frequency from one generation to the next that then result in a new set of phenotypes in the following generation. That&#8217;s R = h^2 S. There&#8217;s also a derivation of Fisher&#8217;s Fundamental Theorem of Natural Selection at one locus with two alleles.<\/li>\n<li>Association mapping &#8211; A very cursory introduction to the principles of association mapping, including some notes on 2-locus population genetics.<\/li>\n<\/ol>\n<p>I expect to get the notes on genomic prediction written next weekend. Once I do, I&#8217;ll also be posting an updated one-volume version of the notes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>I just added three more sets of notes to the website: Resemblance among relatives &#8211; The mathematical underpinnings of how we use resemblance among relatives to estimate components of the genetic variance when we don&#8217;t know the underlying genes. Evolution of quantitative traits &#8211; The mathematics of how selection on phenotypes results in changes in &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/2019\/01\/19\/notes-on-resemblance-among-relatives-evolution-of-quantitative-traits-and-association-mapping\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Notes on resemblance among relatives, evolution of quantitative traits, and association mapping&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-361","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/posts\/361","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/comments?post=361"}],"version-history":[{"count":1,"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/posts\/361\/revisions"}],"predecessor-version":[{"id":362,"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/posts\/361\/revisions\/362"}],"wp:attachment":[{"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/media?parent=361"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/categories?post=361"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/darwin.eeb.uconn.edu\/uncommon-ground\/eeb348\/wp-json\/wp\/v2\/tags?post=361"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}