I just added three more sets of notes to the website:
- Resemblance among relatives – The mathematical underpinnings of how we use resemblance among relatives to estimate components of the genetic variance when we don’t know the underlying genes.
- Evolution of quantitative traits – The mathematics of how selection on phenotypes results in changes in allele frequency from one generation to the next that then result in a new set of phenotypes in the following generation. That’s R = h^2 S. There’s also a derivation of Fisher’s Fundamental Theorem of Natural Selection at one locus with two alleles.
- Association mapping – A very cursory introduction to the principles of association mapping, including some notes on 2-locus population genetics.
I expect to get the notes on genomic prediction written next weekend. Once I do, I’ll also be posting an updated one-volume version of the notes.