First set of molecular evolution notes are posted

We shift gears on Tuesday and start our survey of molecular evolution. We’ll start with a review of the kinds of molecular variation that population geneticists have studied over the last 50 years, then we’ll discuss the neutral theory and some of the ways it’s been modified to fit our increasingly sophisticated understanding of molecular variation. After spring break Nora will talk about some of the ways we can detect selection on nucleotide sequences and about the evolution of multigene families. When I get back we’ll talk about how to use data from molecular markers to make inferences about the recent evolutionary history of individuals and populations, and we’ll finish with a very brief discussion of how the explosion of data that is coming with high-throughput sequencing is changing our approach to understanding evolutionary processes in populations.

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