I'm not going to try to summarize the article in today's Independent by Julia Whitley, but here are the first two paragraphs and a link. Read the whole thing. It's very well done.
In the final stages of dehydration the body shrinks, robbing youth from the young as the skin puckers, eyes recede into orbits, and the tongue swells and cracks. Brain cells shrivel and muscles seize. The kidneys shut down. Blood volume drops, triggering hypovolemic shock, with its attendant respiratory and cardiac failures. These combined assaults disrupt the chemical and electrical pathways of the body until all systems cascade toward death.
Such is also the path of a dying species. Beyond a critical point, the collective body of a unique kind of mammal or bird or amphibian or tree cannot be salvaged, no matter the first aid rendered. Too few individuals spread too far apart, or too genetically weakened, are susceptible to even small natural disasters: a passing thunderstorm; an unexpected freeze; drought. At fewer than 50 members, populations experience increasingly random fluctuations until a kind of fatal arrhythmia takes hold. Eventually, an entire genetic legacy, born in the beginnings of life on earth, is removed from the future. (source)
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