Wahlund Effect and F-statistics

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Instructions


Interpreting the results

Genotype frequencies within each population are calculated according to the standard formulas:

freq(AA)=p2(1-f) + pf
freq(Aa)=2p(1-p)(1-f)
freq(Aa)=(1-p)2(1-f) + (1-p)f

Expected frequencies across the sample of populations are calculated according to Hardy-Weinberg expectations using the average allele frequency, i.e.

freq(AA)=P2
freq(Aa)=2P(1-P)
freq(aa)=(1-P)2

where

P=sum(pi)/n .

Observed genotype frequencies across the sample of populations are calculated from the average genotype frequency across populations.

Fis = f (from the listbox above)
Fst = Var(p)/P(1-P)
1-Fit = (1-Fis)(1-Fst)

where

Var(p) = sum(pi - P)2/n .

Remember that Fit is also equal to

1 - (obs. heterozygosity)/(2P(1-P))

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Last modified: Wed Jan 20 16:55:06 EST 1999