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Introduction

I didn't make a big deal of it in what we just went over, but in deriving the Jukes-Cantor equation I used the phrase ``substitution rate'' instead of the phrase ``mutation rate.'' As a preface to what is about to follow, let me explain the difference.

Mutation rates and substitution rates are obviously related related--substitutions can't happen unless mutations occur, after all--, but it's important to remember that they refer to different processes.



Kent Holsinger 2012-10-30