Several people have asked for clarification on the bonus question. Let me see if I can state the question in a way that makes my intent clearer.
What frequency of homozygotes would you expect in the population if the allele frequencies you just estimated are characteristic of the population and genotypres are in Hardy-Weinberg proportions? Suppose that you didn't know there was a null allele, i.e., you assumed that those individuals who are homozygous null were bad samples that could be ignored. What frequency of "homozygotes", i.e., phenotypes you'd score as homozygous even if they really aren't, would you expect to find in your sample?
Let me know if that doesn't help, and I'll try again.
What frequency of homozygotes would you expect in the population if the allele frequencies you just estimated are characteristic of the population and genotypres are in Hardy-Weinberg proportions? Suppose that you didn't know there was a null allele, i.e., you assumed that those individuals who are homozygous null were bad samples that could be ignored. What frequency of "homozygotes", i.e., phenotypes you'd score as homozygous even if they really aren't, would you expect to find in your sample?
Let me know if that doesn't help, and I'll try again.
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