Inbreeding and self-fertilization

Today I'll start by illustrating a case where Beyesian inference provides a real advantage, estimating allele frequencies in the ABO blood group system.

  1. R script (multinomial.R)
  2. JAGS script (multinomial.jags)
Then we'll start violating the assumptions underlying my derivation of the Hardy-Weinberg principle, and we'll start with a topic that is near and dear to my heart: inbreeding. I spent the first 15-20 years of my life developing theoretical models intended to help us understand when self-fertilization would evolve, but the most important reason for spending some time talking about inbreeding is that understanding it is essential to understanding how population geneticists describe the genetic structure of populations.

I'll give a brief overview of Project #1 during lecture, but Nora will provide more background during lab.

Project #1

Online notes

Inbreeding and self-fertilization

Associated readings

Schoen, D.J., and M.T. Clegg. 1985. The influence of flower color on outcrossing rate and male reproductive success in Ipomoea purpurea. Evolution 39:1242-1249. link

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